I wrote a feature article on revolutionary new imaging methods such as STED (STimulated Emission Depletion) microscopy and SRS (Stimulated Raman Scattering), and the first atomic resolution protein structure determined by cryo-electron microscopy alone. STED, for instance, invented by Stefan Hell in Göttingen, manages to bypass Abbe's diffraction limit, which was considered an unremovable obstacle for more than a century. New methods developed by Sunney Xie at Harvard can coax light signals from molecules that aren't normally fluorescent.
This feature should be out today in
Windows on the nanoworld
Chemistry & Industry, No. 15, pp 20-22