Friday, August 31, 2007

isotopes saga continued

Back in March I reported how researchers think that a diet enriched in heavy isotopes could fend off aging:
http://www.rsc.org/chemistryworld/News/2007/March/22030703.asp

This made a bit of a splash in the general media. But the discussion is also going on in the scientific journals, see the latest issue of Trends in Biotechnology:

Heavy isotopes to avert ageing?
Vadim V. Demidov
Center for Advanced Biotechnology, Boston University, 36 Cummington St., Boston, MA 02215, USA
Oxidative modifications of cellular components by free
radicals are thought to be the cause of ageing and ageassociated
diseases. Extensive prior research has aimed
to lessen such damage by counteracting the free-radical
oxidizers with antioxidants, but there have been no
attempts to protect the oxidizer-targeted biomolecules
by making them more stable against oxidation. A recent
paper describes an original and promising method based
on the use of non-radioactive heavy isotopes, which
might enable living cells to resist the free-radical oxidation
and consequently allow us to live a healthier,
longer life.


TRENDS in Biotechnology
Vol.25 No.9, p. 371-375

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